Dr. Dingbo Lin

Area of study: Human Nutrition
Email: dingbo@ksu.edu
Website: Homepage

“Our lab works to understand molecular mechanisms of phytochemicals in prevention and/or delay of onset of leukemia, which, in turn, may lead to the development of efficient, low cost and long-term safe dietary regimens. We have demonstrated that water soluble phytochemicals from the wolfberry fruit, have dual functions in leukemia cell death. Wolfberry phytochemicals not only function as antioxidants, but as cellular signaling molecules as well. The wolfberry phytochemicals induce leukemia cell death through synergic regulation of body energy homeostasis, oxidative stress, and cellular inflammatory responses. These findings, for the first time, bring us completely novel pictures of dietary prevention of leukemia. We will be investigating how water soluble wolfberry phytochemicals protect against leukemia in transgenic animals and even in humans. Further studies on identification of major active components may also help to develop novel complementary therapeutic agents and/or dietary regimens for cancer prevention and treatment.”