Dr. Ho Leung Ng
Our lab uses experimental and computational biophysics to discover new drugs for cancer and immunology. Our most advanced projects involve the 1) characterization and development of T-cell receptor mimic antibodies for immuno-oncology, 2) developing allosteric inhibitors against the estrogen producing enzyme, aromatase, for treating breast cancer, and 3) developing agonists and antagonists against the immunoregulatory receptor, RORgamma, for treating autoimmune disorders and cancer. We collaborate closely with researchers in clinical research, medicinal chemistry, and industry. A strength of our lab is the ability to perform cutting edge research in both experimental and computational science.