Dr. Emily McLaurin
We design nanoparticle sensors that glow different colors with changes in key cancer growth and death indicators such as oxygen, glucose, and temperature. Nanoparticle-based heating methods, such as plasmonic photothermal therapy and hyperthermia, are emerging therapeutic methods for drug delivery and cancer cell death. Knowledge of the actual temperatures during therapy is vital for improvement of these therapeutics by preventing healthy tissue damage due to prolonged use of therapy, or therapy at temperatures that are too high. Using our nanoparticle optical thermometers, we can obtain real-time feedback to define the actual thermal conduits required for destruction of different types of tumors, ultimately during in vivo experiments.