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Johnson Cancer Research Center

Dr. Duy Hua

Department: Chemistry
Departmental Website

“A class of quinoline molecules (code name PQ), exhibited gap junctional enhancement activity, was discovered in our laboratory. Through the collaborative study with Dr. Thu A. Nguyen, it was found that various PQ compounds possess potent inhibitory activities against T47D breast cancer cells via the enhancement of gap junction activity. Active PQ compounds reduce xenograft breast tumors bearing mice and eradicated tumor formation of spontaneous transgenic mammary mice.”